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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1353398
Species: Homo sapiens
RGD Object: Gene
Symbol: ATG5
Name: autophagy related 5
Acc ID: CHEBI:28939
Term: N-acetyl-L-cysteine
Definition: An N-acetyl-L-amino acid that is the N-acetylated derivative of the natural amino acid L-cysteine.
Chemical ID: MESH:D000111
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ATG5multiple interactionsEXP 6480464CTDAcetylcysteine inhibits the reaction [Acrolein results in increased expression of ATG5 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of ATG5 mRNA]; Acetylcysteine inhibits the reaction [Butyric Acid results in increased expression of ATG5 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of ATG5 mRNA]; Acetylcysteine inhibits the reaction [Vorinostat promotes the reaction [ATG5 protein binds to ATG12 protein]]PMID:20543569 PMID:28600122 PMID:29307831 PMID:30205151 PMID:33146789
ATG5multiple interactionsISOAtg5 (Mus musculus)6480464CTDAcetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of ATG5 mRNA]; Acetylcysteine inhibits the reaction [Zinc Oxide analog results in increased expression of ATG5 mRNA]PMID:24614525 PMID:33462182
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