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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1349475
Species: Homo sapiens
RGD Object: Gene
Symbol: HSPA1A
Name: heat shock protein family A (Hsp70) member 1A
Acc ID: CHEBI:28939
Term: N-acetyl-L-cysteine
Definition: An N-acetyl-L-amino acid that is the N-acetylated derivative of the natural amino acid L-cysteine.
Chemical ID: MESH:D000111
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HSPA1Amultiple interactionsEXP 6480464CTDAcetylcysteine inhibits the reaction [elesclomol results in increased expression of HSPA1A mRNA]; Acetylcysteine inhibits the reaction [Hypochlorous Acid results in increased expression of HSPA1A protein]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased expression of HSPA1A mRNA]PMID:12231548 PMID:16324719 PMID:18723479
HSPA1Amultiple interactionsISOHspa1a (Rattus norvegicus)6480464CTDAcetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of HSPA1A protein]PMID:36813253
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