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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735742
Species: Mus musculus
RGD Object: Gene
Symbol: Ccnb1
Name: cyclin B1
Acc ID: CHEBI:28925
Term: mechlorethamine
Definition: A nitrogen mustard that has formula C5H11Cl2N.
Chemical ID: MESH:D008466
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ccnb1decreases activityISOCCNB1 (Homo sapiens)6480464CTDMechlorethamine results in decreased activity of CCNB1 proteinPMID:8463339
Ccnb1multiple interactionsISOCCNB1 (Homo sapiens)6480464CTDMechlorethamine results in decreased activity of [CCNB1 protein binds to CDK1 protein]; Pentoxifylline inhibits the reaction [Mechlorethamine results in decreased activity of [CCNB1 protein binds to CDK1 protein]]PMID:8463339
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