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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2628
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fosl2
Name: FOS like 2, AP-1 transcription factor subunit
Acc ID: CHEBI:28925
Term: mechlorethamine
Definition: A nitrogen mustard that has formula C5H11Cl2N.
Chemical ID: MESH:D008466
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fosl2increases expressionISOFosl2 (Mus musculus)6480464CTDMechlorethamine results in increased expression of FOSL2 proteinPMID:31639410
Fosl2multiple interactionsISOFOSL2 (Homo sapiens)6480464CTDFOSL2 protein affects the reaction [Mechlorethamine results in increased secretion of CXCL8 protein]PMID:31639410
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