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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1309353
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mrc1
Name: mannose receptor, C type 1
Acc ID: CHEBI:28925
Term: mechlorethamine
Definition: A nitrogen mustard that has formula C5H11Cl2N.
Chemical ID: MESH:D008466
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mrc1increases expressionEXP 6480464CTDMechlorethamine results in increased expression of MRC1 proteinPMID:26273949
Mrc1increases expressionISOMrc1 (Mus musculus)6480464CTDMechlorethamine results in increased expression of MRC1 proteinPMID:30060251
Mrc1multiple interactionsISOMrc1 (Mus musculus)6480464CTDSFTPD gene mutant form promotes the reaction [Mechlorethamine results in increased expression of MRC1 protein]PMID:30060251
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