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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1318374
Species: Homo sapiens
RGD Object: Gene
Symbol: SIRT1
Name: sirtuin 1
Acc ID: CHEBI:28898
Term: P(1),P(5)-bis(5'-adenosyl) pentaphosphate
Definition: A diadenosyl pentaphosphate having the two 5'-adenosyl residues attached at the P(1)- and P(5)-positions.
Chemical ID: MESH:C012275
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SIRT1multiple interactionsISOSirt1 (Rattus norvegicus)6480464CTDP(1),P(5)-di(adenosine-5'-)pentaphosphate analog inhibits the reaction [[Nitrites co-treated with Oxygen deficiency] results in increased expression of SIRT1 mRNA]PMID:22892143
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