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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3310
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pfkfb4
Name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
Acc ID: CHEBI:28885
Term: butan-1-ol
Definition: A primary alcohol that is butane in which a hydrogen of one of the methyl groups is substituted by a hydroxy group. It it produced in small amounts in humans by the gut microbes.
Chemical ID: MESH:D020001
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pfkfb4multiple interactionsISOPFKFB4 (Homo sapiens)6480464CTD[[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of PFKFB4 mRNAPMID:29432896
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