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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731906
Species: Homo sapiens
RGD Object: Gene
Symbol: IL23A
Name: interleukin 23 subunit alpha
Acc ID: CHEBI:28876
Term: melphalan
Definition: A phenylalanine derivative comprising L-phenylalanine having [bis(2-chloroethyl)amino group at the 4-position on the phenyl ring.
Chemical ID: MESH:D008558
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IL23Aincreases expressionISOIl23a (Mus musculus)6480464CTDMelphalan results in increased expression of IL23A proteinPMID:21129433
IL23Amultiple interactionsISOIl23a (Mus musculus)6480464CTDTCRB gene mutant form inhibits the reaction [Melphalan results in increased expression of IL23A protein]; TCRD gene mutant form inhibits the reaction [Melphalan results in increased expression of IL23A protein]PMID:21129433
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