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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1614270
Species: Mus musculus
RGD Object: Gene
Symbol: Srxn1
Name: sulfiredoxin 1 homolog (S. cerevisiae)
Acc ID: CHEBI:28869
Term: menadione
Definition: A member of the class of 1,4-naphthoquinones that is 1,4-naphthoquinone which is substituted at position 2 by a methyl group. It is used as a nutritional supplement and for the treatment of hypoprothrombinemia.
Chemical ID: MESH:D024483
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Srxn1increases expressionEXP 6480464CTDVitamin K 3 results in increased expression of SRXN1 mRNAPMID:25270620
Srxn1increases expressionISOSRXN1 (Homo sapiens)6480464CTDVitamin K 3 results in increased expression of SRXN1 mRNAPMID:23410634
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