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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1321241
Species: Homo sapiens
RGD Object: Gene
Symbol: ALS2
Name: alsin Rho guanine nucleotide exchange factor ALS2
Acc ID: CHEBI:28838
Term: lutein
Definition: A carotenol that has formula C40H56O2.
Chemical ID: MESH:D014975
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ALS2decreases expressionISOAls2 (Mus musculus)6480464CTDLutein results in decreased expression of ALS2 mRNAPMID:24865317
ALS2multiple interactionsISOAls2 (Mus musculus)6480464CTD[Cisplatin co-treated with Lutein] results in decreased expression of ALS2 mRNA; [Cisplatin co-treated with Lutein] results in increased expression of ALS2 mRNAPMID:24865317
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