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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68945
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp4a1
Name: cytochrome P450, family 4, subfamily a, polypeptide 1
Acc ID: CHEBI:28834
Term: deoxycholic acid
Definition: A bile acid that is 5beta-cholan-24-oic acid substituted by hydroxy groups at positions 3 and 12 respectively.
Chemical ID: MESH:D003840
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp4a1decreases expressionEXP 6480464CTDDeoxycholic Acid results in decreased expression of CYP4A1 proteinPMID:10453939
Cyp4a1multiple interactionsEXP 6480464CTDUrsodeoxycholic Acid inhibits the reaction [Deoxycholic Acid results in decreased expression of CYP4A1 protein]PMID:10453939
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