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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620349
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ptgs2
Name: prostaglandin-endoperoxide synthase 2
Acc ID: CHEBI:28824
Term: stigmasterol
Definition: A 3beta-sterol that consists of 3beta-hydroxystigmastane having double bonds at the 5,6- and 22,23-positions.
Chemical ID: MESH:D013265
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptgs2multiple interactionsISORGD:7310076480464CTDStigmasterol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] Stigmasterol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]

PMID:23535395
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