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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620298
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcg5
Name: ATP binding cassette subfamily G member 5
Acc ID: CHEBI:28824
Term: stigmasterol
Definition: A 3beta-sterol that consists of 3beta-hydroxystigmastane having double bonds at the 5,6- and 22,23-positions.
Chemical ID: MESH:D013265
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcg5decreases expressionISORGD:7322196480464CTDStigmasterol results in decreased expression of ABCG5 mRNA

PMID:23454145
Abcg5multiple interactionsISORGD:7322196480464CTD[Stigmasterol co-treated with KNG1 protein modified form] results in decreased expression of ABCG5 mRNA [Stigmasterol co-treated with Oligomycins] results in decreased expression of ABCG5 mRNA [Stigmasterol co-treated with Rotenone] results in decreased expression of ABCG5 mRNA

PMID:23454145
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