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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2681
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gfra1
Name: GDNF family receptor alpha 1
Acc ID: CHEBI:28824
Term: stigmasterol
Definition: A 3beta-sterol that consists of 3beta-hydroxystigmastane having double bonds at the 5,6- and 22,23-positions.
Chemical ID: MESH:D013265
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gfra1multiple interactionsISORGD:106356480464CTD[bisphenol A co-treated with Stigmasterol] results in decreased expression of GFRA1 mRNA NR1H4 gene mutant form inhibits the reaction [[bisphenol A co-treated with Stigmasterol] results in decreased expression of GFRA1 mRNA] Stigmasterol inhibits the reaction [GW 4064 results in decreased expression of GFRA1 mRNA]

PMID:30245210
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