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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621065
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Csf2
Name: colony stimulating factor 2
Acc ID: CHEBI:28821
Term: piperine
Definition: A N-acylpiperidine that is piperidine substituted by a (1E,3E)-1-(1,3-benzodioxol-5-yl)-5-oxopenta-1,3-dien-5-yl group at the nitrogen atom. It is an alkaloid isolated from the plant Piper nigrum.
Chemical ID: MESH:C008922
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Csf2decreases expressionISOCSF2 (Homo sapiens)6480464CTDpiperine results in decreased expression of CSF2 mRNAPMID:15531295
Csf2decreases secretionISOCSF2 (Homo sapiens)6480464CTDpiperine results in decreased secretion of CSF2 proteinPMID:15531295
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