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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3371
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pparg
Name: peroxisome proliferator-activated receptor gamma
Acc ID: CHEBI:28819
Term: naringin
Definition: A disaccharide derivative that is (S)-naringenin substituted by a 2-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage.
Chemical ID: MESH:C005274
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ppargmultiple interactionsEXP 6480464CTD[naringin co-treated with Pioglitazone] inhibits the reaction [Quinolinic Acid results in decreased expression of PPARG mRNA]; naringin inhibits the reaction [Quinolinic Acid results in decreased expression of PPARG mRNA]PMID:30130594
Ppargmultiple interactionsISOPparg (Mus musculus)6480464CTDnaringin affects the reaction [LEPR protein affects the expression of PPARG protein]; naringin inhibits the reaction [Dietary Fats results in increased expression of PPARG mRNA]PMID:16427799 PMID:22198281
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