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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735868
Species: Homo sapiens
RGD Object: Gene
Symbol: NQO1
Name: NAD(P)H quinone dehydrogenase 1
Acc ID: CHEBI:28794
Term: coumarin
Definition: A chromenone having the keto group located at the 2-position.
Chemical ID: MESH:C030123
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:104736480464CTDcoumarin results in increased expression of NQO1 mRNA, coumarin results in increased expression of NQO1 protein

PMID:11309284, PMID:17311802
increases expressionISORGD:25036480464CTDcoumarin results in increased expression of NQO1 mRNA

PMID:18480146
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.