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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1352010
Species: Homo sapiens
RGD Object: Gene
Symbol: CDK2
Name: cyclin dependent kinase 2
Acc ID: CHEBI:28794
Term: coumarin
Definition: A chromenone having the keto group located at the 2-position.
Chemical ID: MESH:C030123
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CDK2decreases expressionEXP 6480464CTDcoumarin analog results in decreased expression of CDK2 mRNAPMID:32578917
CDK2increases phosphorylationEXP 6480464CTDcoumarin results in increased phosphorylation of CDK2 proteinPMID:35688186
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