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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 13921310
Species: Sus scrofa
RGD Object: Gene
Symbol: FOS
Name: Fos proto-oncogene, AP-1 transcription factor subunit
Acc ID: CHEBI:28790
Term: serotonin
Definition: A primary amino compound that is the 5-hydroxy derivative of tryptamine.
Chemical ID: MESH:D012701
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
FOSincreases expressionEXP 6480464CTDSerotonin results in increased expression of FOS mRNA Serotonin results in increased expression of FOS protein

PMID:11426759
FOSmultiple interactionsEXP 6480464CTDsarpogrelate inhibits the reaction [Serotonin results in increased expression of FOS mRNA] sarpogrelate inhibits the reaction [Serotonin results in increased expression of FOS protein]

PMID:11426759
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