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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1348738
Species: Homo sapiens
RGD Object: Gene
Symbol: ITGA2
Name: integrin subunit alpha 2
Acc ID: CHEBI:28790
Term: serotonin
Definition: A primary amino compound that is the 5-hydroxy derivative of tryptamine.
Chemical ID: MESH:D012701
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ITGA2multiple interactionsISOItga2 (Mus musculus)6480464CTDITGA2 protein promotes the reaction [[Dinoprostone co-treated with Serotonin] results in increased import of Calcium]; TRPV4 protein promotes the reaction [ITGA2 protein promotes the reaction [[Dinoprostone co-treated with Serotonin] results in increased import of Calcium]]PMID:18234883
ITGA2multiple interactionsISOItga2 (Rattus norvegicus)6480464CTDITGA2 protein results in increased susceptibility to [KNG1 protein modified form co-treated with TAC1 protein modified form co-treated with Serotonin co-treated with Dinoprostone co-treated with Histamine]PMID:18234883
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