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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735962
Species: Homo sapiens
RGD Object: Gene
Symbol: APOA1
Name: apolipoprotein A1
Acc ID: CHEBI:28787
Term: nitroglycerin
Definition: A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.
Chemical ID: MESH:D005996
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
APOA1decreases expressionISOApoa1 (Rattus norvegicus)6480464CTDNitroglycerin results in decreased expression of APOA1 mRNAPMID:12102619
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