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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737278
Species: Mus musculus
RGD Object: Gene
Symbol: Slc22a1
Name: solute carrier family 22 (organic cation transporter), member 1
Acc ID: CHEBI:28757
Term: fructose
Definition: A ketohexose that is an isomer of glucose.
Chemical ID: MESH:D005632
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc22a1decreases expressionISOSlc22a1 (Rattus norvegicus)6480464CTDFructose results in decreased expression of SLC22A1 mRNA; Fructose results in decreased expression of SLC22A1 proteinPMID:19605544
Slc22a1multiple interactionsISOSlc22a1 (Rattus norvegicus)6480464CTDAllopurinol inhibits the reaction [Fructose results in decreased expression of SLC22A1 mRNA]; Allopurinol inhibits the reaction [Fructose results in decreased expression of SLC22A1 protein]; Quercetin inhibits the reaction [Fructose results in decreased expression of SLC22A1 mRNA]; Quercetin inhibits the reaction [Fructose results in decreased expression of SLC22A1 protein]; Rutin inhibits the reaction [Fructose results in decreased expression of SLC22A1 mRNA]; Rutin inhibits the reaction [Fructose results in decreased expression of SLC22A1 protein]PMID:19605544
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