GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CAT | decreases activity | ISO | Cat (Rattus norvegicus) | 6480464 | CTD | Fructose results in decreased activity of CAT protein | PMID:23707192 PMID:30710622 | CAT | decreases expression | ISO | Cat (Rattus norvegicus) | 6480464 | CTD | Fructose results in decreased expression of CAT mRNA; Fructose results in decreased expression of CAT protein | PMID:11817707 PMID:20470786 | CAT | multiple interactions | ISO | Cat (Rattus norvegicus) | 6480464 | CTD | [Fructose co-treated with Streptozocin] results in decreased activity of CAT protein; [Hydrochlorothiazide co-treated with Fructose] results in decreased activity of CAT protein; APLN protein modified form inhibits the reaction [Fructose results in decreased activity of CAT protein]; Metformin inhibits the reaction [[Fructose co-treated with Streptozocin] results in decreased activity of CAT protein]; vanillin inhibits the reaction [[Fructose co-treated with Streptozocin] results in decreased activity of CAT protein] | PMID:23707192 PMID:30710622 PMID:33823243 | CAT | multiple interactions | ISO | Cat (Mus musculus) | 6480464 | CTD | [Dietary Fats co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Ethanol] results in decreased expression of CAT protein; [Dietary Fats co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose] results in decreased expression of CAT protein; [Fructose co-treated with Dietary Fats] results in decreased activity of CAT protein; troxerutin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in decreased activity of CAT protein] | PMID:28916335 PMID:37271273 | | ||||||||||||||||||||||
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