GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | IL1B | increases expression | ISO | Il1b (Rattus norvegicus) | 6480464 | CTD | Fructose results in increased expression of IL1B protein | PMID:15885234 PMID:22426011 PMID:24491314 PMID:26358169 PMID:30480462 PMID:31005848 | IL1B | increases secretion | ISO | Il1b (Rattus norvegicus) | 6480464 | CTD | Fructose results in increased secretion of IL1B protein | PMID:25679220 | IL1B | multiple interactions | ISO | Il1b (Mus musculus) | 6480464 | CTD | [Fructose co-treated with Ethanol] results in increased expression of IL1B mRNA | PMID:26858005 | IL1B | multiple interactions | ISO | Il1b (Rattus norvegicus) | 6480464 | CTD | [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of IL1B protein]; [Dietary Fats co-treated with Fructose] results in increased expression of IL1B protein; [gadolinium chloride co-treated with Fructose co-treated with Copper deficiency] results in decreased expression of IL1B mRNA; Allopurinol inhibits the reaction [Fructose results in increased expression of IL1B protein]; geraniol inhibits the reaction [Fructose results in increased expression of IL1B protein]; geraniol inhibits the reaction [Fructose results in increased secretion of IL1B protein]; Pioglitazone inhibits the reaction [Fructose results in increased secretion of IL1B protein]; PTMA protein inhibits the reaction [Fructose results in increased expression of IL1B protein]; Quercetin inhibits the reaction [Fructose results in increased expression of IL1B protein]; Rutin inhibits the reaction [Fructose results in increased expression of IL1B protein]; tributylhexadecylphosphonium bromide inhibits the reaction [Fructose results in increased expression of IL1B protein] | PMID:15885234 PMID:22426011 PMID:24491314 PMID:25679220 PMID:25813056 PMID:26358169 PMID:31005848 PMID:34939712 | | ||||||||||||||||||||||
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