GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cyp2e1 | decreases expression | ISO | Cyp2e1 (Mus musculus) | 6480464 | CTD | Fructose results in decreased expression of CYP2E1 protein | PMID:28257781 | Cyp2e1 | increases expression | ISO | Cyp2e1 (Mus musculus) | 6480464 | CTD | Fructose results in increased expression of CYP2E1 protein | PMID:26858005 | Cyp2e1 | multiple interactions | ISO | Cyp2e1 (Mus musculus) | 6480464 | CTD | [Dietary Fats co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Ethanol] results in increased expression of CYP2E1 mRNA; [Dietary Fats co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Ethanol] results in increased expression of CYP2E1 protein; [Dietary Fats co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose] results in increased expression of CYP2E1 mRNA; Ethanol promotes the reaction [Fructose results in increased expression of CYP2E1 protein] | PMID:26858005 PMID:37271273 | | ||||||||||||||||||||||
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