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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1552545
Species: Mus musculus
RGD Object: Gene
Symbol: Pnpla2
Name: patatin-like phospholipase domain containing 2
Acc ID: CHEBI:28757
Term: fructose
Definition: A ketohexose that is an isomer of glucose.
Chemical ID: MESH:D005632
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pnpla2increases expressionEXP 6480464CTDFructose results in increased expression of PNPLA2 proteinPMID:28257781
Pnpla2decreases expressionISOPnpla2 (Rattus norvegicus)6480464CTDFructose results in decreased expression of PNPLA2 mRNAPMID:31661889
Pnpla2multiple interactionsISOPnpla2 (Rattus norvegicus)6480464CTDbisphenol A promotes the reaction [Fructose results in decreased expression of PNPLA2 mRNA]; Fructose promotes the reaction [bisphenol A results in decreased expression of PNPLA2 mRNA]PMID:31661889
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