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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1343574
Species: Homo sapiens
RGD Object: Gene
Symbol: TXNIP
Name: thioredoxin interacting protein
Acc ID: CHEBI:28757
Term: fructose
Definition: A ketohexose that is an isomer of glucose.
Chemical ID: MESH:D005632
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TXNIPincreases expressionISOTxnip (Rattus norvegicus)6480464CTDFructose results in increased expression of TXNIP proteinPMID:24491314
TXNIPmultiple interactionsISOTxnip (Rattus norvegicus)6480464CTDAllopurinol inhibits the reaction [Fructose results in increased expression of TXNIP protein]; Quercetin inhibits the reaction [Fructose results in increased expression of TXNIP protein]PMID:24491314
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