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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737386
Species: Homo sapiens
RGD Object: Gene
Symbol: BDKRB2
Name: bradykinin receptor B2
Acc ID: CHEBI:28748
Term: doxorubicin
Definition: An anthracycline antibiotic that has formula C27H29NO11.
Chemical ID: MESH:D004317
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
BDKRB2decreases expressionEXP 6480464CTDDoxorubicin results in decreased expression of BDKRB2 mRNAPMID:29803840
BDKRB2increases expressionISOBdkrb2 (Mus musculus)6480464CTDDoxorubicin results in increased expression of BDKRB2 mRNAPMID:37409694
BDKRB2multiple interactionsISOBdkrb2 (Mus musculus)6480464CTDBDKRB2 protein affects the reaction [Doxorubicin results in decreased expression of NOS3 protein]; BDKRB2 protein affects the reaction [Doxorubicin results in increased expression of FABP4 protein]; BDKRB2 protein affects the reaction [Doxorubicin results in increased expression of GPT protein]; BDKRB2 protein affects the reaction [Doxorubicin results in increased expression of NOS2 protein]PMID:37409694
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