GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tomm20 | decreases expression | ISO | TOMM20 (Homo sapiens) | 6480464 | CTD | Doxorubicin results in decreased expression of TOMM20 protein | PMID:31226464 | Tomm20 | decreases response to substance | ISO | TOMM20 (Homo sapiens) | 6480464 | CTD | TOMM20 mRNA results in decreased susceptibility to Doxorubicin | PMID:16322897 | Tomm20 | increases expression | ISO | TOMM20 (Homo sapiens) | 6480464 | CTD | Doxorubicin results in increased expression of TOMM20 mRNA | PMID:29803840 | Tomm20 | multiple interactions | ISO | TOMM20 (Homo sapiens) | 6480464 | CTD | 3-methyladenine inhibits the reaction [Doxorubicin results in decreased expression of TOMM20 protein]; pepstatin inhibits the reaction [Doxorubicin results in decreased expression of TOMM20 protein]; PQQ Cofactor inhibits the reaction [Doxorubicin results in decreased expression of TOMM20 protein] | PMID:31226464 | |
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