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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732721
Species: Mus musculus
RGD Object: Gene
Symbol: Trpc6
Name: transient receptor potential cation channel, subfamily C, member 6
Acc ID: CHEBI:28748
Term: doxorubicin
Definition: An anthracycline antibiotic that has formula C27H29NO11.
Chemical ID: MESH:D004317
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Trpc6increases expressionISOTrpc6 (Rattus norvegicus)6480464CTDDoxorubicin results in increased expression of TRPC6 proteinPMID:28495616
Trpc6multiple interactionsISOTrpc6 (Rattus norvegicus)6480464CTDsalvianolic acid B inhibits the reaction [Doxorubicin results in increased expression of TRPC6 protein]PMID:28495616
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