GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | PDPK1 | decreases response to substance | EXP | | 6480464 | CTD | PDPK1 protein results in decreased susceptibility to Doxorubicin | PMID:16782806 | PDPK1 | decreases expression | ISO | Pdpk1 (Mus musculus) | 6480464 | CTD | Doxorubicin results in decreased expression of PDPK1 protein | PMID:19429709 PMID:26450947 | PDPK1 | multiple interactions | ISO | Pdpk1 (Mus musculus) | 6480464 | CTD | 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [resveratrol inhibits the reaction [Doxorubicin results in decreased expression of PDPK1 protein]]; resveratrol inhibits the reaction [Doxorubicin results in decreased expression of PDPK1 protein]; sirtinol inhibits the reaction [resveratrol inhibits the reaction [Doxorubicin results in decreased expression of PDPK1 protein]] | PMID:26450947 | |
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