Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731267
Species: Homo sapiens
RGD Object: Gene
Symbol: PKIA
Name: cAMP-dependent protein kinase inhibitor alpha
Acc ID: CHEBI:28748
Term: doxorubicin
Definition: An anthracycline antibiotic that has formula C27H29NO11.
Chemical ID: MESH:D004317
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects response to substanceEXP 6480464CTDPKIA protein affects the susceptibility to Doxorubicin

PMID:16217747
decreases expressionEXP 6480464CTDDoxorubicin results in decreased expression of PKIA mRNA

PMID:29803840
decreases expressionISORGD:7312686480464CTDDoxorubicin results in decreased expression of PKIA mRNA

PMID:25896364
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.