GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tmsb4x | decreases response to substance | ISO | TMSB4X (Homo sapiens) | 6480464 | CTD | TMSB4X protein results in decreased susceptibility to Doxorubicin | PMID:16364925 | Tmsb4x | increases expression | ISO | TMSB4X (Homo sapiens) | 6480464 | CTD | Doxorubicin results in increased expression of TMSB4X mRNA | PMID:29803840 | Tmsb4x | multiple interactions | ISO | TMSB4X (Homo sapiens) | 6480464 | CTD | TMSB4X protein inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; TMSB4X protein inhibits the reaction [Doxorubicin results in increased cleavage of and results in increased activity of CASP9 protein] | PMID:16364925 | |
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