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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620457
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Stk17b
Name: serine/threonine kinase 17b
Acc ID: CHEBI:28748
Term: doxorubicin
Definition: An anthracycline antibiotic that has formula C27H29NO11.
Chemical ID: MESH:D004317
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Stk17bmultiple interactionsISOStk17b (Mus musculus)6480464CTDIloprost inhibits the reaction [PTGS2 gene mutant form promotes the reaction [Doxorubicin results in increased expression of STK17B mRNA]]; PTGS2 gene mutant form promotes the reaction [Doxorubicin results in increased expression of STK17B mRNA]PMID:16617129
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