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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3380
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ppp2ca
Name: protein phosphatase 2 catalytic subunit alpha
Acc ID: CHEBI:28748
Term: doxorubicin
Definition: An anthracycline antibiotic that has formula C27H29NO11.
Chemical ID: MESH:D004317
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ppp2caincreases expressionEXP 6480464CTDDoxorubicin results in increased expression of PPP2CA mRNAPMID:19915844
Ppp2camultiple interactionsEXP 6480464CTDRazoxane inhibits the reaction [Doxorubicin results in increased expression of PPP2CA mRNA]PMID:19915844
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