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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3142
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Myl3
Name: myosin light chain 3
Acc ID: CHEBI:28748
Term: doxorubicin
Definition: An anthracycline antibiotic that has formula C27H29NO11.
Chemical ID: MESH:D004317
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Myl3affects expressionISOMYL3 (Homo sapiens)6480464CTDDoxorubicin affects the expression of MYL3 mRNA; Doxorubicin affects the expression of MYL3 proteinPMID:29385562 PMID:29803840
Myl3decreases expressionISOMYL3 (Homo sapiens)6480464CTDDoxorubicin results in decreased expression of MYL3 mRNAPMID:28940058
Myl3increases expressionISOMyl3 (Mus musculus)6480464CTDDoxorubicin results in increased expression of MYL3 proteinPMID:21251210
Myl3multiple interactionsISOMyl3 (Mus musculus)6480464CTDsodium nitrate inhibits the reaction [Doxorubicin results in increased expression of MYL3 protein]PMID:21251210
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