GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Pmaip1 | increases expression | EXP | | 6480464 | CTD | Doxorubicin results in increased expression of PMAIP1 mRNA | PMID:16018998 PMID:26873546 PMID:27155237 PMID:29653124 PMID:34713381 | Pmaip1 | increases expression | ISO | PMAIP1 (Homo sapiens) | 6480464 | CTD | Doxorubicin results in increased expression of PMAIP1 mRNA | PMID:17653088 PMID:30031762 | Pmaip1 | increases expression | ISO | Pmaip1 (Rattus norvegicus) | 6480464 | CTD | Doxorubicin results in increased expression of PMAIP1 mRNA | PMID:34713381 | Pmaip1 | increases response to substance | ISO | PMAIP1 (Homo sapiens) | 6480464 | CTD | PMAIP1 protein results in increased susceptibility to Doxorubicin | PMID:20856197 | Pmaip1 | multiple interactions | ISO | PMAIP1 (Homo sapiens) | 6480464 | CTD | [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with Doxorubicin] results in increased expression of PMAIP1 protein; [[[Doxorubicin co-treated with 2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid] results in increased phosphorylation of ABL1 protein] which results in increased expression of TP73 protein] which results in increased expression of PMAIP1 protein; [[Doxorubicin co-treated with 2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid] results in increased expression of TP73 protein] which results in increased expression of PMAIP1 mRNA; [[Doxorubicin co-treated with 2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid] results in increased expression of TP73 protein] which results in increased expression of PMAIP1 protein; [PI103 co-treated with Doxorubicin] results in increased expression of PMAIP1 protein; [YAP1 protein promotes the reaction [[Doxorubicin co-treated with 2,5,7,8-tetramethyl-2R-(4R,8R,12-trimethyltridecyl)chroman-6-yloxy acetic acid] results in increased expression of TP73 protein]] which results in increased expression of PMAIP1 protein; PMAIP1 protein results in increased susceptibility to [Doxorubicin co-treated with PI103] | PMID:20856197 PMID:21214929 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |