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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1565398
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Col6a1
Name: collagen type VI alpha 1 chain
Acc ID: CHEBI:28748
Term: doxorubicin
Definition: An anthracycline antibiotic that has formula C27H29NO11.
Chemical ID: MESH:D004317
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Col6a1affects expressionISOCOL6A1 (Homo sapiens)6480464CTDDoxorubicin affects the expression of COL6A1 mRNAPMID:29803840
Col6a1increases expressionISOCol6a1 (Mus musculus)6480464CTDDoxorubicin results in increased expression of COL6A1 mRNAPMID:15033991
Col6a1multiple interactionsISOCol6a1 (Mus musculus)6480464CTD[[MT1 protein co-treated with MT2 protein] affects the susceptibility to Doxorubicin] which affects the expression of COL6A1 mRNAPMID:21040762
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