RGD Gene Chemical Interaction Report

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	1560956
Species:	Rattus norvegicus
RGD Object:	Gene
Symbol:	Anxa10
Name:	annexin A10

Acc ID:	CHEBI:28748
Term:	doxorubicin
Definition:	An anthracycline antibiotic that has formula C27H29NO11.
Chemical ID:	MESH:D004317

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases expression	ISO	RGD:1318990	6480464	CTD	Doxorubicin results in increased expression of ANXA10 mRNA	PMID:26873546
multiple interactions	ISO	RGD:1318990	6480464	CTD	[Doxorubicin co-treated with Dexrazoxane] results in decreased expression of ANXA10 mRNA	PMID:26873546

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.

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