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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1354369
Species: Homo sapiens
RGD Object: Gene
Symbol: HEY2
Name: hes related family bHLH transcription factor with YRPW motif 2
Acc ID: CHEBI:28748
Term: doxorubicin
Definition: An anthracycline antibiotic that has formula C27H29NO11.
Chemical ID: MESH:D004317
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HEY2decreases expressionEXP 6480464CTDDoxorubicin results in decreased expression of HEY2 mRNAPMID:29803840
HEY2increases expressionISOHey2 (Mus musculus)6480464CTDDoxorubicin results in increased expression of HEY2 mRNAPMID:28318631
HEY2multiple interactionsISOHey2 (Mus musculus)6480464CTDNiclosamide inhibits the reaction [Doxorubicin results in increased expression of HEY2 mRNA]PMID:28318631
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