GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CD40LG | decreases response to substance | EXP | | 6480464 | CTD | CD40LG protein results in decreased susceptibility to Doxorubicin | PMID:16545138 | CD40LG | multiple interactions | EXP | | 6480464 | CTD | CD40LG protein inhibits the reaction [Doxorubicin promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]]; Doxorubicin promotes the reaction [[CD40LG protein co-treated with IL4 protein] results in increased expression of H2AX protein modified form]; Doxorubicin promotes the reaction [[CD40LG protein co-treated with IL4 protein] results in increased expression of TP53 protein] | PMID:16545138 PMID:27634759 | | ||||||||||||||||||||||
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