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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1350913
Species: Homo sapiens
RGD Object: Gene
Symbol: BNIP3
Name: BCL2 interacting protein 3
Acc ID: CHEBI:28748
Term: doxorubicin
Definition: An anthracycline antibiotic that has formula C27H29NO11.
Chemical ID: MESH:D004317
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
BNIP3decreases expressionEXP 6480464CTDDoxorubicin results in decreased expression of BNIP3 mRNAPMID:22908232
BNIP3increases expressionEXP 6480464CTDDoxorubicin results in increased expression of BNIP3 mRNAPMID:29803840
BNIP3increases expressionISOBnip3 (Mus musculus)6480464CTDDoxorubicin results in increased expression of BNIP3 mRNAPMID:19001878 PMID:25896364
BNIP3multiple interactionsISOBnip3 (Mus musculus)6480464CTDPARP1 protein promotes the reaction [Doxorubicin results in increased expression of BNIP3 mRNA]PMID:19001878
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