GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CASP4 | increases activity | ISO | Casp4 (Rattus norvegicus) | 6480464 | CTD | Doxorubicin results in increased activity of CASP5 protein | PMID:19801490 | CASP4 | increases expression | ISO | Casp4 (Mus musculus) | 6480464 | CTD | Doxorubicin results in increased expression of CASP4 mRNA | PMID:26873546 | CASP4 | multiple interactions | ISO | Casp4 (Mus musculus) | 6480464 | CTD | [Doxorubicin co-treated with Dexrazoxane] results in decreased expression of CASP4 mRNA | PMID:26873546 | CASP4 | multiple interactions | ISO | Casp4 (Rattus norvegicus) | 6480464 | CTD | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [NRG1 protein inhibits the reaction [Doxorubicin results in increased activity of CASP5 protein]]; NRG1 protein inhibits the reaction [Doxorubicin results in increased activity of CASP5 protein] | PMID:19801490 | | ||||||||||||||||||||||
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