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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1320891
Species: Mus musculus
RGD Object: Gene
Symbol: Ndc80
Name: NDC80 kinetochore complex component
Acc ID: CHEBI:28748
Term: doxorubicin
Definition: An anthracycline antibiotic that has formula C27H29NO11.
Chemical ID: MESH:D004317
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ndc80affects response to substanceISONDC80 (Homo sapiens)6480464CTDNDC80 protein affects the susceptibility to DoxorubicinPMID:16217747
Ndc80decreases expressionISONDC80 (Homo sapiens)6480464CTDDoxorubicin results in decreased expression of NDC80 mRNAPMID:30031762
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