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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1320607
Species: Homo sapiens
RGD Object: Gene
Symbol: TLR1
Name: toll like receptor 1
Acc ID: CHEBI:28748
Term: doxorubicin
Definition: An anthracycline antibiotic that has formula C27H29NO11.
Chemical ID: MESH:D004317
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TLR1increases expressionISOTlr1 (Rattus norvegicus)6480464CTDDoxorubicin results in increased expression of TLR1 mRNAPMID:27181935
TLR1multiple interactionsISOTlr1 (Rattus norvegicus)6480464CTDFungal Polysaccharides inhibits the reaction [Doxorubicin results in increased expression of TLR1 mRNA]PMID:27181935
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