GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Sfn | affects response to substance | ISO | SFN (Homo sapiens) | 6480464 | CTD | SFN protein affects the susceptibility to Doxorubicin | PMID:26894857 | Sfn | decreases expression | ISO | SFN (Homo sapiens) | 6480464 | CTD | Doxorubicin results in decreased expression of SFN mRNA | PMID:24816189 | Sfn | increases expression | ISO | SFN (Homo sapiens) | 6480464 | CTD | Doxorubicin results in increased expression of SFN protein | PMID:24816189 | Sfn | multiple interactions | ISO | SFN (Homo sapiens) | 6480464 | CTD | TP53 protein mutant form affects the reaction [Doxorubicin results in decreased expression of SFN mRNA]; TP53 protein mutant form affects the reaction [Doxorubicin results in increased expression of SFN protein] | PMID:24816189 | | ||||||||||||||||||||||
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