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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1309921
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tnnc1
Name: troponin C1, slow skeletal and cardiac type
Acc ID: CHEBI:28748
Term: doxorubicin
Definition: An anthracycline antibiotic that has formula C27H29NO11.
Chemical ID: MESH:D004317
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tnnc1affects expressionISOTNNC1 (Homo sapiens)6480464CTDDoxorubicin affects the expression of TNNC1 proteinPMID:29385562
Tnnc1decreases expressionISOTnnc1 (Mus musculus)6480464CTDDoxorubicin results in decreased expression of TNNC1 proteinPMID:19801490
Tnnc1increases expressionISOTNNC1 (Homo sapiens)6480464CTDDoxorubicin results in increased expression of TNNC1 mRNAPMID:29803840
Tnnc1multiple interactionsISOTnnc1 (Mus musculus)6480464CTDNRG1 protein affects the reaction [Doxorubicin results in decreased expression of TNNC1 protein]PMID:19801490
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