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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1309280
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rfc5
Name: replication factor C subunit 5
Acc ID: CHEBI:28748
Term: doxorubicin
Definition: An anthracycline antibiotic that has formula C27H29NO11.
Chemical ID: MESH:D004317
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rfc5affects response to substanceISORFC5 (Homo sapiens)6480464CTDRFC5 protein affects the susceptibility to DoxorubicinPMID:16217747
Rfc5decreases expressionISORFC5 (Homo sapiens)6480464CTDDoxorubicin results in decreased expression of RFC5 mRNAPMID:29803840
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