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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11131
Species: Mus musculus
RGD Object: Gene
Symbol: Ppia
Name: peptidylprolyl isomerase A
Acc ID: CHEBI:28748
Term: doxorubicin
Definition: An anthracycline antibiotic that has formula C27H29NO11.
Chemical ID: MESH:D004317
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ppiaincreases expressionISOPPIA (Homo sapiens)6480464CTDDoxorubicin results in increased expression of PPIA mRNAPMID:29803840
Ppiaincreases oxidationISOPpia (Rattus norvegicus)6480464CTDDoxorubicin results in increased oxidation of PPIA proteinPMID:28818578
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