GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Myc | increases expression | EXP | | 6480464 | CTD | Doxorubicin results in increased expression of MYC mRNA | PMID:36227756 | Myc | multiple interactions | EXP | | 6480464 | CTD | Doxorubicin promotes the reaction [AZD 6244 results in decreased expression of MYC protein] | PMID:17876044 | Myc | affects response to substance | ISO | MYC (Homo sapiens) | 6480464 | CTD | MYC protein affects the susceptibility to Doxorubicin | PMID:18802399 | Myc | decreases expression | ISO | MYC (Homo sapiens) | 6480464 | CTD | Doxorubicin results in decreased expression of MYC mRNA | PMID:11585056 PMID:16001973 PMID:29803840 | Myc | increases expression | ISO | Myc (Rattus norvegicus) | 6480464 | CTD | Doxorubicin results in increased expression of MYC mRNA | PMID:20211217 | Myc | increases response to substance | ISO | MYC (Homo sapiens) | 6480464 | CTD | MYC protein results in increased susceptibility to Doxorubicin | PMID:21324178 | Myc | multiple interactions | ISO | MYC (Homo sapiens) | 6480464 | CTD | [BIN1 protein binds to and results in decreased activity of MYC protein] which results in increased susceptibility to Doxorubicin; [Curcumin co-treated with Doxorubicin] affects the expression of MYC mRNA; [Doxorubicin co-treated with cordycepin] results in decreased expression of MYC protein; [Doxorubicin co-treated with tanshinone] affects the expression of MYC protein; WAY-262611 affects the reaction [[Doxorubicin co-treated with tanshinone] affects the expression of MYC protein] | PMID:15911101 PMID:21447800 PMID:32886829 PMID:35186504 | | ||||||||||||||||||||||
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